Radiological evidence of Goldenhar syndrome in a paleopathological case from a South German ossuary.

We investigated the skull of a juvenile living in Southern Germany between 1400 and 1800 A.D. A remarkable hemifacial microsomia led to further detailed computed tomographic examination especially of the petrous bone revealing a total bony atresia of the external auditory canal as well as distinct anomalies of the middle ear on the same side. The combination of these findings strongly suggests the diagnosis of Goldenhar syndrome. This very heterogeneous syndrome affects primarily aural, ocular, oral and mandibular development, whereby the constellation of anomalies indicate their origin at approximately 30-45 days of gestation, caused by genetic or intrauterine factors. Despite the lack of clinical information and the absence of soft tissue it was possible to perform a differential diagnosis in this palaeopathological case. Thereby, the use of modern modalities of image reconstructions in this computed tomographic clearly enhanced the supposed diagnosis.

[Diagnosis and treatment of frostbite]. / Diagnostik und Behandlung von Erfrierungen.

Pathophysiology, clinical picture with grading and in some cases controversial possibilities of treatment are described. We report on our experience in treatment of 21 cases of frostbite on hands and feet. Widening by DSA of the diagnostic spectrum of late sequelae is emphasized.

[Percutaneous fine needle biopsy of lymph nodes (author's transl)]. / Die perkutane Feinnadelbiopsie von Lymphknoten.

Following lymphography, 76 lymph nodes were punctured percutaneously using a fine needle in 23 patients and an aspiration biopsy was performed. This simple procedure provided cytological comfirmation in cases of doubtful lymphograms. Systematic puncture of representative lymph nodes in the area of metastatic spread may at times be able to replace a staging operation.